A source from 1917 I stumbled upon...

Thanks, Google Books.

The Supernatural in Modern English Fiction
by Dorothy Scarborough

"No supernaturalism is incredible if it is expressed in technical terminology, and no miracle will be rejected if its setting be in a laboratory.  One peculiar thing about modern scientific thought in its reaction upon fiction is that it is equally effective in realism, such as shown in teh naturalisti novels of Zola, the plays of Brieux and others, and in supernaturalism, as in the work of H.G. Wells, for instance, where the ghostly is grafted on to cold realism" (Scarborough 252). 

She lists a bunch more texts that use the Fourth Dimension, if I need to add to that section of Chapter 2. 

She calls Dr. Jekyll and Mr. Hyde "chemical supernaturalism" (Scarborough 268).  She refers to what he drinks as "the magic drug." 

""The Invisible Man, by H.G. Wells, shows an unusual application of chemistry to ghostly fiction that gives a peculiar effect of reality because its style is that of scientific realism.  By experimentation with drugs a man finds a combination that will render living tissue absolutely invisible...This modern method of transferring to science the idea of invisibilty so prominent in connection with ghosts, showing the invisibility as the result of a chemical compound, not of supernatural intervention, affecting a living man not a spirit, makes the effect of supernaturalism more vivid even than in the case of ghosts" (Scarborough 269).

"This type shows a strange effect of realism in supernaturalism, because of the scientific methods, for supernaturalism imposed on material things produces an effect of verisimilitude not gained int eh realm of pure spirit.  Too intellectually cold for the purposes of poetry, too abstract and elusive for presentation in drama, and too removed by its association with the fantastic aspects of investigation and the curiosities of science to be very appropriate tragedy, which has hitherto been the chief medium of expressing the dramatic supernatural, science finds its fitting expression in prose fiction" (Scarborough 280).